ea0028oc3.5 | Obesity, thyroid and Addison's disease | SFEBES2012
Pearce Simon
, Mitchell Anna
, Bennett Stuart
, King Philip
, Chandran Sukesh
, Nag Sath
, Chen Shu
, Furmaniak Jadwiga
, Isaacs John
, Vaidya Bijay
Background: A diagnosis of Addisons disease means lifelong dependence on daily glucocorticoid and mineralocorticoid therapy and is associated with increased morbidity and mortality, as well as a risk of unexpected adrenal crisis. We wished to explore whether immunomodulatory therapy at an early stage of autoimmune Addisons disease could lead to preservation or improvement in adrenal steroidogenic function.Design: We conducted an open-label, p...